International Journal of Clinical Biochemistry and Research
  • Year: 2017
  • Volume: 4
  • Issue: 2

Association of 25 OH-Vitamin D and hs-CRPin adults with Essential Hypertension

  • Author:
  • M. Prasad1,, P. Aruna2, D.R. Rajeswari3, K. Ramalingam4, J.N. Naidu5
  • Total Page Count: 4
  • Page Number: 178 to 181

1PHD Scholar, Dept. of Biochemistry, Narayana Medical College and Hospital, Nellore

2Assistant Professor, Dept. of Biochemistry, ACSR Govt. Medical College and Hospital, Nellore

3Professor, Dept. of Biochemistry, Narayana Medical College and Hospital, Nellore

4Associate Professor, Dept. of Biochemistry, Narayana Medical College and Hospital, Nellore

5Professor & Head, Dept. of Biochemistry, Narayana Medical College and Hospital, Nellore

*Corresponding Author: Email: m.prasadnaidu@ymail.com

Online published on 14 June, 2017.

Abstract

Essential hypertensionis a typical example of complex, multifactorial trait and a well studied risk factor for cardiovascular disease. hs-CRP is well known marker of inflammation resulting in atherosclerosis and cardiovascular disease. Recent studies showed that 25-OH-vitamin-D has ananti-inflammatory role and decreased levels may increase the cardiovascular risk in subjects with essential hypertension. The study included 30 adults both male and female with essential hypertension (Systolic Blood Pressure ≥ 140 mm Hg and Diastolic Blood Pressure ≥ 90 mm Hg) as cases. 30 age and sex matched healthy individuals both male & female between the age group of 24–60 years attending General OPD, General Medicine Department, NMCH, were taken as controls. The inverse relationship of Vitamin D with hs-CRP levels leads to cardiovascular risk in subjects with essential hypertension.

Keywords

Essential hypertension, hs-CRP, Vitamin D and Inflammation