1PHD Scholar, Dept. of Biochemistry, Narayana Medical College and Hospital, Nellore
2Assistant Professor, Dept. of Biochemistry, ACSR Govt. Medical College and Hospital, Nellore
3Professor, Dept. of Biochemistry, Narayana Medical College and Hospital, Nellore
4Associate Professor, Dept. of Biochemistry, Narayana Medical College and Hospital, Nellore
5Professor & Head, Dept. of Biochemistry, Narayana Medical College and Hospital, Nellore
*Corresponding Author: Email: m.prasadnaidu@ymail.com
Online published on 14 June, 2017.
Essential hypertensionis a typical example of complex, multifactorial trait and a well studied risk factor for cardiovascular disease. hs-CRP is well known marker of inflammation resulting in atherosclerosis and cardiovascular disease. Recent studies showed that 25-OH-vitamin-D has ananti-inflammatory role and decreased levels may increase the cardiovascular risk in subjects with essential hypertension. The study included 30 adults both male and female with essential hypertension (Systolic Blood Pressure ≥ 140 mm Hg and Diastolic Blood Pressure ≥ 90 mm Hg) as cases. 30 age and sex matched healthy individuals both male & female between the age group of 24–60 years attending General OPD, General Medicine Department, NMCH, were taken as controls. The inverse relationship of Vitamin D with hs-CRP levels leads to cardiovascular risk in subjects with essential hypertension.
Essential hypertension, hs-CRP, Vitamin D and Inflammation