International Journal of Clinical Biochemistry and Research
  • Year: 2017
  • Volume: 4
  • Issue: 2

Evaluation of hsCRP, Insulin and Insulin resistance in Polycystic Ovarian Syndrome

1P.G. Student, Dept. of Biochemistry, Dr. S. N. Medical College, Jodhpur, Rajasthan

2Professor, Dept. of Biochemistry, Dr. S. N. Medical College, Jodhpur, Rajasthan

*Corresponding Author: Email: sapnajangir24@gmail.com

Online published on 14 June, 2017.

Abstract

Polycystic Ovarian Syndrome consists of a constellation of metabolic abnormalities and is now well recognised having a major effect throughout life on the reproductive, metabolic and cardiovascular health of affected women.

The present study was conducted to evaluate hsCRP, insulin and insulin resistance levels in PCOS patients.

30 PCOS subjects in the age group of 18 to 34 years and 25 age-matched healthy women as controls were evaluated.

Serum hsCRP, insulin, insulin resistance, BMI and waist-to-hip ratio were significantly elevated (p<0.0001) in PCOS cases when compared with controls. There was a positive correlation between hsCRP and insulin (p=0.2001) and hsCRP and insulin resistance (p = 0.127) in PCOS patients.

PCOS women have added risk of complications of cardiovascular disease and Diabetes mellitus.

Keywords

Cardiovascular disease, Diabetes mellitus, hsCRP, Insulin resistance, Polycystic Ovarian Syndrome, Inflammation