1Assistant Professor, Dept. of Biochemistry, JIIU's Indian Institute of Medical Science and Research, Warudi, Maharashtra
2Associate Professor, Dept. of Biochemistry, Government Medical College, Aurangabad, Maharashtra, India
*Corresponding Author: Email: aghadesunita@gmail.com
Online published on 2 January, 2019.
The Polycystic Ovary Syndrome (PCOS) is one of the most common reproductive endocrine disorders, affecting 5–10% of women in the reproductive age. Insulin resistance is the hallmark of this disorder. PCOS has been epidemiologically linked to an increased risk for type 2 diabetes mellitus and cardiovascular diseases. The present study was planned to study glycated hemoglobin (HbA1c) and uric acid level in patients of PCOS
The study comprised of 60 women with PCOS as cases and 60 healthy females as controls. HbA1c and uric acid level were measured in all participants
Glycated hemoglobin and serum uric acid were significantly increased in PCOS group and showed positive correlation with body mass index and waist: hip ratio. The prevalence of raised HbA1c was 40% in PCOS women
In our study we found significant alterations in HbA1c and uric acid level in cases of PCOS. Early identification of these changes and timely intervention can reduce morbidity due to type 2 diabetes mellitus and cardiovascular diseases in PCOS. This will help to redefine the paradigms of PCOS care in India.
Cardiovascular Disease, HbA1c, PCOS, Type 2 Diabetes Mellitus, Uric Acid
