1Assistant Professor, Dept. of Biochemistry, Velammal Medical College Hospital & RI, Madurai, Tamil Nadu,
2Associate Professor, Dept. of Biochemistry, Tagore Medical College Hospital, Chennai, Tamil Nadu
3Tutor, Dept. of Community Medicine, PES Institute of Medical Sciences and Research, Kupam, Andra Pradesh, India,
4Director, Professor & HOD, Dept. of Biochemistry, Madras Medical College, Chennai, Tamil Nadu, India
*Corresponding Author: Email: desigamani@tagoremch.com
Online published on 2 January, 2019.
Aim of the present study is to analyse the nutritional status of iodine among pregnant women by measuring urinary excretion and do the correlation with thyroid hormone and auto antibodies
one hundred pregnant women with third trimester gestation and one hundred agematched non-pregnant were included in study
Urinary Iodine excretion and serum TSH, fT4, fT3, AMA and ATG were estimated were estimated for case and control groups. The mean urinary iodine excretion concentration (UIC) in pregnant women was 290.17±91.71 μg/L. Excess urinary iodine excretion was found in 69%. There were elevated serum AMA levels in 36 pregnant women and that positive correlated with excess iodine
The pregnant women had no iodine deficiency, rather had high urinary iodine concentrations indicating more than adequate iodine intake. The excess urinary iodine level may tiger the thyroid auto antibody.
Urinary iodine excretion (UIE), thyroid stimulating hormone (TSH), free thyroxine (fT4), free triiodothyronine (fT3), anti-microsomal antibody (AMA), anti-thyroglobulin antibody (ATA), pregnancy, iodine excess
