A rare case of systemic sarcoidosis with cutaneous and sublingual salivary gland involvement

Sarcoidosis is a systemic granulomatous disorder of unidentified etiology and pathologically characterized by non-caseating granulomas. Majority of patients (∼30%) have cutaneous lesions, exhibit different manifestations depending on diverse races whereas some patients develop systemic involvement. Diagnosis is based on a compatible clinical and radiological presentation and evidence of non-caseating granulomas. Here, we report a rare case of cutaneous sarcoidosis with a nodulocystic swelling on the floor of the mouth, which upon biopsy revealed a dense, non-caseating granulomatous infiltrate in the dermis. Identification of systemic involvement was based on laboratory investigations, slit skin smear, sputum smear for acid-fast bacilli (AFB), chest X-ray, pulmonary function tests, computerized tomography (CT), ultrasound of abdomen and radiological examination. The patient was treated successfully and is being reviewed once every two weeks till date.