Indian Journal of Clinical and Experimental Dermatology
  • Year: 2016
  • Volume: 2
  • Issue: 4

Fever with rash; Role of an untold history in clinching the diagnosis

  • Author:
  • Prashanth R. Kamath1,, Radhika S. Bhat2, Parag Patel3, Amin Basil Cholakundan3
  • Total Page Count: 3
  • Page Number: 171 to 173

1Assistant Professor, Dept. of Dermatology, AD Institute of Medical Sciences, Mangaluru

2Senior Resident, Dept. of Dermatology, AD Institute of Medical Sciences, Mangaluru

3Junior Resident, Dept. of Dermatology, AD Institute of Medical Sciences, Mangaluru

*Corresponding Author: Email: drprashanthkamath@gmail.com

Online published on 14 June, 2017.

Abstract

Dapsone is a potent antimicrobial and anti-inflammatory compound, which is mainly used in the treatment of leprosy, neutrophilic dermatoses and a variety of blistering skin diseases. It is known to cause a severe adverse drug reaction presenting with fever, rash and multiorgan involvement known as Dapsone Hypersensitivity Syndrome (DHS). Here we report a case of near fatal fever, rash, and hepatitis secondary to dapsone.

Keywords

Dapsone Hypersensitivity, Dapsone Syndrome, Leprosy, Multidrug Treatment