Indian Journal of Clinical and Experimental Ophthalmology
  • Year: 2015
  • Volume: 1
  • Issue: 4

The role of Rebamipide ophthalmic suspension in management of dry eye disease

  • Author:
  • Laxmi Dorennavar1,, Rajendra P Maurya2, Virendra P Singh3, Mahendra K Singh3, Kamya Sharma4, Ritika Sharma1
  • Total Page Count: 6
  • Page Number: 191 to 196

1Junior Resident, Department of Ophthalmology, Institute of Medical Sciences, Banaras Hindu University, Varanasi

2Assistant Professor, Department of Ophthalmology, Institute of Medical Sciences, Banaras Hindu University, Varanasi

3Professor, Department of Ophthalmology, Institute of Medical Sciences, Banaras Hindu University, Varanasi

4Senior Resident, Department of Ophthalmology, Institute of Medical Sciences, Banaras Hindu University, Varanasi

*Corresponding Author: Email: seematalks@gmail.com

Online published on 4 February, 2016.

Abstract

Review of the drug Rebamipide, an ophthalmic suspension, in the treatment of dry eye and other ocular surface disorders.

An extensive literature search was done on articles published in various ophthalmic journals to review the work on the latest drug rebamipide and its role in treating dry eye and other ocular surface disorders.

Rebamipide is a novel drug for the treatment of dry eye disorders. It is a mucin-secretogogue, has a cytoprotective, anti-inflammatory effect and also suppresses the detrimental oxygen free radicals and helps in faster healing of epithelium. No major side effect has been noticed apart from dysguesia.

Rebamipide is the latest drug introduced in the treatment of dry eye. It seems to be a safe and effective treatment in chronic and severe forms of dry eye particularly due to mucus deficiency.

Keywords

Dry eye, Goblet cell, Microvilli, Rebamipide, Tear film