Indian Journal of Clinical and Experimental Ophthalmology
  • Year: 2017
  • Volume: 3
  • Issue: 4

Analysis of effect of trabeculectomy in adult primary open angle glaucoma patients using spectral domain optical coherence tomography in Indian population

1Associate Professor, Dept. of Ophthalmology, North Bengal Medical College, Siliguri

2Clinical Tutor, Dept. of Ophthalmology, Nil Ratan Sircar Medical College, Kolkata

3Post Graduate Trainee, Dept. of Ophthalmology, Regional Institute of Ophthalmology, Kolkata

*Corresponding Author: Email: nabanita_br@yahoo.co.in

Online published on 3 April, 2018.

Abstract

To evaluate the change in retinal nerve fiber layer thickness (RNFL) using Optical Coherence Tomography after trabeculectomy in adult patients with primary open angle glaucoma (POAG).

A total of 40 eyes (30 patients) with POAG, uncontrolled on medical management were enrolled. Average and quadrant wise RNFL thickness were measured pre and post operatively at 1 week, 1 and 3 months. Data was analysed using SPSS software.

Intraocular pressure (IOP) reduced from 28.55+ 8.47 mm Hg, 14.8+ 5.97 mm Hg at 1 week, 14.25 + 4.47 mm Hg at 1 month, 14.9 +4.8 mm Hg at 3 months (p<0.0001)). There was no statistically significant change in RNFL level noted at 1 or 3 months (p=0.1847). Visual function (MD and PSD) also remained unchanged. RNFL thickness had significant negative correlation with age, IOP and pattern standard deviation. We divided the patients in two groups < 50 years and >50 years and analyzed the data but no statistically significant changes were found.

In this study, post glaucoma filtration surgery, there was significant lowering of IOP but no difference in RNFL thickness, visual field parameters in adult POAG patients.

Keywords

Optical coherence tomography, Trabeculectomy, RNFL thickness variation