1Assistant Professor, Department of Biochemistry, Sri Jayadeva Institute of Cardiovascular Science & Research, Bangalore, Karnataka
2Assistant Professor, Department of Biochemistry, Karpaga Vinayaga Institute of Medical Science, Kanchipuram, Tamilnadu
3Assistant Professor, Department of Biochemistry, Dr B R Ambedkar Medical College, Bangalore, Karnataka
4Assistant Professor, Department of Community Medicine, S.S. Institute of Medical Sciences & Research Centre, Davangere, Karnataka
5PG/Tutor, Department of Biochemistry, Dr B R Ambedkar Medical College, Bangalore, Karnataka
6Professor & HOD, Department of Biochemistry, Dr B R Ambedkar Medical College, Bangalore, Karnataka
Online published on 7 October, 2013.
Alcoholism is a major threat to public health in both developed and developing countries. Over last 30–40 years alcohol consumption has increased in quantity and frequency. Alcohol use predisposes subjects to changes in lipid profile which are associated with coronary risk.
30 alcoholic males were compared with 30 non alcoholic males. Alcohol drinking history was assessed by interview and questionnaire and lipid profile was done measuring total cholesterol, triglycerides, HDL, VLDL & LDL.
There were significant rise in TC, TGL, HDL, LDL and VLDL of chronic alcoholics compared with non alcoholics with p value 0.001, <0.001, 0.004, 0.290, <0.001, respectively. Lipid profile was compared among moderate and heavy drinkers and found increased levels of TC, TGL, LDL & VLDL with p value <0.001, 0.001, 0.002 & 0.001 respectively in heavy drinkers. There is decrease in HDL cholesterol among heavy drinkers compared with moderate drinkers, p value 0.011 which is significant. But remains elevated compared to non alcoholics.
This study shows that alcohol intake increases the level of lipid parameters. Moderate alcohol intake increases HDL cholesterol whereas heavy alcohol consumption increases TC,TGL,LDL & VLDL and decreases HDL.
Lipid Profile, Moderate Drinkers, Heavy Drinkers
