1Associate Profeesor, Department of Biochemistry, U.P. RIMS & R Saifai, Etawah, U.P.
2Associate Professor, Department of Ophthalmology, U.P. RIMS & R Saifai, Etawah, U.P.
3Demonstrator, Department of Microbiology, U.P. RIMS & R Saifai, Etawah, U.P.
4Professor, Department of Biochemistry, U.P. RIMS & R Saifai, Etawah, U.P.
5Additional Professor, Department of Biochemistry, U.P. RIMS & R Saifai, Etawah, U.P.
6Additional Professor, Department of Anatomy, U.P. RIMS & R Saifai, Etawah, U.P.
*Corresponding author: Pradeep Sharma, Associate Professor, Department of Biochemistry, U. P. Rural Institute of Medical Science & Research, Saifai, Etawah (U.P.), Mobile No. 9027155457. E Mail Address: pradeepsharma2001@rediffmail.com
Online published on 31 January, 2015.
Osteoarthritis of knee joints is a disease of old age female sex. It is very common in post menopausal females. It is characterized by narrowing of space in joints due to inflammation. The exact mechanism of inflammation is not clear. Estrogen hormone plays a bone protective effect of knee osteoarthritic disease.
The present study is being carried out in 150 female subject of age group 40–60 years suffering from osteoarthritis of knee joints and 50 normal healthy control female subjects of same age group.
A correlation is made between TNF-α and estrogen hormone and found significant inverse correlation (< 0.001) in postmenopausal osteoarthritic female patients as compared to normal healthy control subjects.
Estrogen hormone, Tumor necrosis factor-alpha (TNF-α)
