1Associate Professor, Dept. of Skin & V.D., Bharati Vidyapeeth Deemed University Medical College & Hospital, Sangli
2Ex Head, Dept. & Professor of Skin & V.D., Grant Medical College, Sir JJ Groups of Hospital, Mumbai
3Associate Professor, Community Medicine, ESIC MC & PGIMSR, Rajajinagar, Bangalore, Karnataka
4Assistant Professor, Dept. of Pediatrics, Government Medical College, Miraj
Online published on 31 January, 2015.
The increase in the number of HIV infected patients and the progression of the disease into the AIDS has stimulated widespread attention.
HIV primarily affects the immune system with involvement of lymph nodes. The present study was undertaken to know the clinical features, causes of lymphadenopathy & associated opportunistic infections in HIV infected Indian population.
The observational study was carried out in the department of Skin and Venereology in Grant Medical College. Sir JJ Groups of hospital, Mumbai between the period from Jan 2000 to Dec. 2002. A total of 60 clinically and serologically diagnosed HIV positive cases with lymphadenopathy were included in the study. Demographic and clinical history of all cases was taken followed by thorough clinical examination and investigations were done. On the basis of clinical findings and investigations, final diagnosis was made.
Out of 60 cases majority of the patients were in age groups of 31–40 years, male: female ratio was 4:1. Cervical lymph node was the commonest site of lymph node enlargement. Patients had discrete, matted and solitary lymphadenopathy respectively (70%, 28%, 2%). 51% cases showed, tuberculous lymphadenitis, suggestive of being most common cause in lymph node swelling in HIV. Oral candidiasis was the commonest opportunistic infection in HIV infected patients.
HIV, Lymphadenopathy, Opportunistic Infection