1Lecturer, Department of Anaesthesiology, Uttar Pradesh Rural Institute of Medical Sciences, Saifai, Etawah
2Senior Resident, Department of Anaesthesiology, Uttar Pradesh Rural Institute of Medical Sciences, Saifai, Etawah
3Associate Professor, Depart of Medicine, Uttar Pradesh Rural Institute of Medical Sciences, Saifai, Etawah
Dexmedetomidine is used as spinal anesthetic adjuvant for potentiating the actions of local anaesthetics. We devised this study to compare the effects of 3, 5 and 10 μg dexmedetomidine on 3 ml of 0.75% isobaric ropivacaine in patients undergoing inguinal hernia repair. 64 patients were divided into 4 groups. Group 1 was given spinal ropivacaine, while groups 2, 3 and 4 received additional 3, 5, 10 μg dexmedetomidine respectively. Duration of two segment sensory regression (72.25±9.46, 97.63±8.17, 125.63±9.96, 125.63±9.96 minutes in groups 1, 2, 3 and 4 respectively), duration of analgesia (156.00±8.40, 278.38±13.69, 356.00±11.84, 441.56±16.62 minutes in groups 1, 2, 3 and 4 respectively), motor block (133.31±10.90, 258.25±23.29, 330.50±22.66, 408.63±19.14 minutes in groups 1, 2, 3 and 4 respectively) and sensory block (188.00±13.26, 188.00±13.26, 384.50±30.85, 487.50±40.60 minutes in groups 1, 2, 3 and 4 respectively) were significantly prolonged in patients receiving dexmedetomidine in a dose dependent manner. Peak sensory block and side effects were unaffected by dexmedetomidine. We conclude that dexmedetomidine prolongs the duration of sensorimotor block and analgesia in a dose dependent manner.
Dexmedetomidine, Spinal Anaesthesia, Ropivacaine
