1Associate Professor, Department of Medicine, Muzaffarnagar Medical College Muzaffarnagar, Uttar Pradesh, India
2Assistant Professor, Department of Medicine, Muzaffarnagar Medical College Muzaffarnagar, Uttar Pradesh, India
3Professor, Department of Biochemistry, Muzaffarnagar Medical College Muzaffarnagar, Uttar Pradesh, India
*Correspondence to: -Dr. Hemant Kumar Sharma Associate Professor, Department of Medicine, Muzaffarnagar Medical College Muzaffarnagar, U.P., India. Tel: +91 9758417852 E-mail: hemantkumarsharma1959@gmail.com
Online published on 15 February, 2017.
Systemic inflammatory activity has turned out to play a key pathogenic role in vascular atherosclerosis, insulin resistance, and type 2 diabetes mellitus (T2DM). Inflammatory biomarkers may therefore be a valuable tool for risk evaluation. Data suggest that High sensitive C reactive protein (hs-CRP) may participate directly in the process of atherogenesis. The analyses were done with 90 type 2 diabetic and 60 non-diabetic individuals. Anthropometric and biochemical parameters were studied to assess the association of hs-CRP with in T2DM. T2DM encompasses-90% of the diabetic subjects, and it is characterized by insulin resistance often accompanied by obesity and dyslipidemia. High sensitive C reactive protein, the golden marker of inflammation was analyzed in diabetic subjects. Serum hs-CRP levels were positively related to anthropometric parameters. Elevated level of hs-CRP in diabetic subjects was observed with insulin resistance and has strong cardio vascular risk marker in these individuals.
Cardio vascular disease (CVD), High sensitive C-reactive protein (hs-CRP), Type 2 diabetic mellitus (T2DM), Insulin resistance (IR)
