1Professor, Department of Medicine, Kerala Medical College, Mangode, Cherpulassery, Palakkad District, Kerala
2Assistant Professor, Department of Medicine, Malabar Medical College, Modakkallur, Atholi, Kozhikode, Kerala
*Correspondence author Dr. U.M. Natarajan Professor, Department of Medicine, Kerala Medical College Hospital Mangode, Cherpulassery, Palakkad District, Kerala
Online published on 15 February, 2017.
Periodontitis plays a central role in complex multifactorial chronic inflammatory diseases and cardiovascular disease (CVD).
To evaluate association between severe generalized periodontitis and subclinical atherosclerosis in young, otherwise systemically healthy individuals.
60 systemically healthy individuals of age between 20–40 years were included. Group I consisted of 30 subjects with healthy periodontal tissue & group II with 30 subjects with severe generalized periodontitis. Ultrasonographic evaluation of bilateral carotid intima media thickness (IMT)at the level of common carotid artery was done.
The overall mean IMT in group I was 0.52±0.07mm and in group II was 0.61±0.07mm. Bivariate analysis considering the binomial IMT (≥0.6) as outcome variable showed odd's ratio=16 for probing depth and clinical attachment loss. Final model of stepwise logistic regression using binomial IMT (> 0.6) as outcome variable showed statistical significance with clinical attachment loss suggesting that, as the clinical attachment loss increases the IMT also increases.
Severe generalised periodontitis is associated with sub-clinical atherosclerosis in young systemically healthy patients.
Periodontitis, Atherosclerosis, carotid intima-media thickness
