Associate Professor, Department of Pathology, Al-Azhar Medical College and Super Specialty Hospital, Thodupuzha, Kumaramangalam, Kerala, India
*Correspondence author: Dr. B Narasimha Rao, Associate Professor, Department of Pathology, Al-Azhar Medical College and Super Specialty Hospital, Thodupuzha, Kumaramangalam, Kerala, India, Email Id: doctorbnr@gmail.com
Online published on 15 February, 2017.
Gallbladder is one of the most commonly encountered specimen in a pathology laboratory. A diverse spectrum of diseases affect the biliary system, often presenting with similar clinical signs and symptoms.
To evaluate the profile of gallbladder diseases and also to determine potential correlations between histopathologic features noted.
This study reviewed all cholecystectomies processed in Department of Pathology of Al Azar super specialty Hospital between June 2014 and July 2016. Gross and histopathologic features of the specimens were reevaluated.
Among 250 patients; 69.9% were women and 30.1% were men. This study found out that fourteen primary gallbladder carcinomas (5.6%) with adenocarcinomas being the most frequent type (78.57%). The rate of cholelithiasis was found as 89.9%. The most common type of gallstones was mixed cholesterol type gallstones with 67.5% followed by black pigment and brown pigment types as 23.83% and 5.89%, respectively. The association of metaplasia with dysplasia and also gallstones were statistically significant (p<0.001, p<0.005). The rate of the gallbladder polyps was 2.6% with the cholesterol polyps being the most common type (56.4%).
Gallbladder diseases often present with similar clinical signs and symptoms and a surgical pathologist should be alert especially of precancerous lesions. With our results, it is concluded that elderly women with longstanding gallstone disease should undergo elective surgery even when no symptoms are present.
Cholelithiasis, Gallbladder diseases, Precancerous conditions, Gallbladder neoplasms
