International Journal of Contemporary Medicine
  • Year: 2017
  • Volume: 5
  • Issue: 1

Sero-prevalence and Co-infection of Hepatitis A & E Virus in Patients with Acute Viral Hepatitis at a Tertiary Care Hospital

  • Author:
  • Swati Salila1,, Suman Kumar1, Kumar Vikram1, Rakesh Kumar2, Shailesh Kumar3, Anima Xess4, S K Shahi4
  • Total Page Count: 4
  • Page Number: 95 to 98

1JR, Department of Microbiology, IGIMS, Patna, Bihar, India

2Asst. Professor, Department of Microbiology, IGIMS, Patna, Bihar, India

3Assoc. Professor, Department of Microbiology, IGIMS, Patna, Bihar, India

4Professor, Department of Microbiology, IGIMS, Patna, Bihar, India

*Corresponding author: -Dr. Swati Salila Junior Resident, Department of Microbioloy, IGIMS, Patna-800014, (M)-8521637372, Email:- dr.swatisalila@gmail.com

Online published on 15 February, 2017.

Abstract

Viral Hepatitis is a global public health problem. India is hyperendemic for Hepatitis A virus (HAV) and Hepatitis E virus (HEV) Enterically transmitted viral hepatitis is common in resource limited countries with limited access to essential water sanitation, hygiene and health services. This study was conducted to determine the prevalence of HAV and HEV in patients presenting with acute viral hepatitis(AVH) and co-infection of HAV and HEV in these patients.

Prevalence of HAV, HEV and co-infection in patients with AVH.

Serum samples of 748 patients with symptoms of AVH were analysed for IgM anti-HAV and IgM anti-HEV for detection of HAV & HEV using ELISA kits.

Seroprevalence of HAV &HEV was 12.7% and 10.02% respectively. The sero-prevalence of both HAV & HEV was 3.07%. The males(88.23%) were affected more than females(11.76%). There was a slight increase in number during the month of August and September.

The increase in prevalence during the monsoon suggests water contamination during these months hence, better water sanitation is recommended. Increased prevalence in males suggest more exposure to outside contaminated food as they travel more for job or business.

Keywords

Acute viral hepatitis, HAV, HEV, coinfection