1Associate Professor, Department of Medicine, Karpagam Faculty of Medical Sciences and Research, Othakkalmandapam, Coimbatore, Tamil Nadu, India
2Assistant Professor, Department of Medicine, Karpagam Faculty of Medical Sciences and Research, Othakkalmandapam, Coimbatore, Tamil Nadu, India
*Corresponding author: Dr. S Ramkumar Associate Professor, Department of Medicine Karpagam Faculty of Medical Sciences and Research, Othakkalmandapam, Coimbatore-641 032, Tamil Nadu, India
Online published on 15 February, 2017.
The role of HbA1c (Glycosylated Hemoglobin) in predicting the outcome of acute coronary syndrome remains largely controversial.
To determine the impact of HbA1c levels on the severity and complications of acute coronary syndrome in non-diabetics.
This prospective study included 80 patients without diabetes mellitus who were admitted to the ICCU with ACS. The diagnosis of ACS was made on the basis of troponin T value, ECG and echocardiograph. Patients were classified according to their HbA1c into two groups: Group 1 HbA1c <5.6, group 2 HbA1c between 5.7 and 6.4. Main outcome measures were ECG changes, trop T value, echo changes, along with the complications.
The mean age of patients was 56.67 years out of which 69% were males and 31% females. Of total, 27% were smokers, 33% were hypertensive, 30% had dyslipidemia and BMI was ≥ 25 kg/m2 in 10% of the subjects. The findings of this study found that increased levels of HbA1c were associated with poorer result in the non-diabetics.
HbA1c is an index of major adverse outcomes in acute coronary syndrome in patients with non diabetics. Assessment of HbA1c levels might progress the risk assessment in patients with ACS.
acute coronary syndrome, HbA1c, non-diabetics
