1Tutor, Department of Physiology, Indira Gandhi Institute of Medical Sciences, Patna
*Corresponding Author: Dr Pooja Sakshi, Tutor (Physiology), IGIMS, Patna, Bihar. Mobile: 9661548621. Email: drpsnhakshi@rediffmail.com
Online published on 18 January, 2018.
Type 2 diabetes mellitus has been a major cause of morbidity and mortality worldwide. It is associated with many complications involving eyes, kidneys, heart and nerves etc. But studies on its pulmonary complications are still facing controversies. So this study is focused on determining whether lung is a target organ for type 2 diabetes mellitus or not.
In this study, we aimed to find the effect of type 2 diabetes on pulmonary function parameters.
This cross sectional study was done to analyze the pulmonary function parameters in 80 type 2 diabetics of age 40–60 years, and compare the findings with that of age and sex matched 80 healthy volunteers (for control) by computerized electronic spirometer (Universal Medical Instruments & Electromedicals Spiromin).
This study clearly showed statistically significant decrease in levels of FVC and FEV1 in type 2 diabetics as compared to controls, whereas FEV1/FVC and PEFR, showed no significant change. The FVC (in L) for diabetics and controls were 3.31±0.7 and 3.96±0.62 respectively with p<0.0001. The FEV1 (in L) for diabetics and controls were 3.07±0.59 and 3.62±0.72 respectively with p<0.0001. Analysis of all parameters was done by independent t-test.
Even though type 2 diabetes patients in this study, had no respiratory symptoms, but they did have underlying subclinical restrictive pattern of lung function. So type 2 diabetes mellitus is associated with restrictive pattern of respiratory abnormality.
Diabetes mellitus, lung function, FVC
