International Journal of Contemporary Medicine
  • Year: 2019
  • Volume: 7
  • Issue: 1

Comparison of Tuberculin Skin Test Versus Newer Quantiferon TB Gold Assay Method in Screening for Latent Tuberculosis Infection in Various High Risk Groups

Associate Professor, Department of Tuberculosis and Reparatory Medicine, C U Shah Medical College, Surendranagar, Gujarat, India

*Corresponding author: Gordhanbhai L, Associate Professor, Department of Tuberculosis and Reparatory Medicine, C U Shah Medical College, Surendranagar, Gujarat, India. Email: researchguide86@gmail.com

Online published on 4 February, 2019.

Abstract

The aim of present study to evaluate the QuantiFERON-TB gold assay and tuberculin skin test to recognize tuberculosis infection amongst tuberculosis patient contact.

A total of 55 tuberculosis patients contacts were utilized for research, blood were pinched and practices by utilizing the QuantiFERON-TB gold assay pursue by insistent management of tuberculin skin test solution in subjects forearm. All accessible associates were asked to giveblood samples for Latent tuberculosis infection intest.

QuantiFERON-TB gold assay distinguish Latent tuberculosis infection with sensitivity of 88.81% and specificity of 89.9%. Tuberculin skin test: Sensitivity 67.9%, Specificity 15.9%.

Equally tuberculin skin test and QuantiFERON-TB gold assay can be utilized to recognize TB disease or Latent tuberculosis infection. The present assessment of tuberculin skin test&QuantiFERON-TB gold assay consequence bears thatQFT-G assay supply additional accurate results than tuberculin skin test in revealing of Latent tuberculosis infection.

Keywords

Communicable disease, Sensitivity, Specificity, Tuberculosis