1Associate Professor, Department of Cardiology, IGIMS, Patna
2Associate Professor, Department of Biochemistry, IGIMS, Patna
3Associate Professor, Department of Pharmacology, IGIMS, Patna
4Professor, Department of Biochemistry, KGMU, Lucknow
5Professor, Department of Cardiology, KGMU, Lucknow
*Corresponding author: Dr. Ravi Vishnu Prasad, Associate Professor, Department of Cardiology, IGIMS, Patna, Bihar-800014. Email: rvpd2004@yahoo.co.in
Online published on 17 July, 2019.
There is limited literature regarding effect of various clinical parameters on TIMI flow in ACS patients who underwent PCI. Also, it is not well known whether oxidative stress which is produced at local site can influence TIMI flow. Our study was done to evaluate role of various clinical parameters and oxidative stress markers on TIMI flow. The TIMI flow showed significant (r= -0.27, p<0.01) inverse relation with the disease severity i.e. as disease progresses, TIMI flow decreases. 100% occlusion showed highest and significant inverse relation with the TIMI flow, followed by LV dysfunction, diabetes, thrombus and least by smoker and ACS. The gender has no relation with the TIMI flow and similar influence on TIMI flow. Pre PCI level of all antioxidants and free radical marker did not show any association (p>0.05) with TIMI flow. Pre PCI scores of TIMI flow are much dependent on clinical characteristics rather than antioxidants and free radical marker.
PCI, OXIDATIVE STRESS, TIMI Flow
