International Journal of Contemporary Medicine

  • Year: 2019
  • Volume: 7
  • Issue: 2

Randomised Control Trial of Dexmedetomidine and Magnesium Sulfate as an Adjuvant to Ropivacaine in Supraclavicular Brachial Plexus Block

  • Author:
  • Saurabh Singh1, Rajesh Raman2,, Gyan Prakash Singh3, Vinita Singh3, Santosh Kumar4, Vaibhav Tewari5
  • Total Page Count: 6
  • Page Number: 39 to 44

1Junior Resident, Dept. of Anesthesiology, KGMU, Lucknow

2Assistant Professor, Dept. of Anesthesiology, KGMU, Lucknow

3Professor, Dept. of Anesthesiology, KGMU, Lucknow

4Professor, Dept. of Orthopedics, KGMU, Lucknow

5Senoir Resident, Dept. of Anesthesiology, KGMU, Lucknow

*Corrosponding Author: Dr Rajesh Raman, Assistant Professor, Dept. of Anesthesiology, King George’s Medical University, Chowk, Lucknow-226003, Uttar Pradesh. Email: ramanrajesh83@gmail.com

Online published on 17 July, 2019.

Abstract

Several adjuvants potentiate peripheral nerve block. We studied effects of adding magnesium sulfate or dexmedetomidine to 20 ml 0.75% ropivacaine for supraclavicular brachial plexus block.

80 patients were divided in four groups, which, in addition to ropivacaine, received: Group A- 1 ml normal saline, Group B- 125 mg magnesium sulfate, Group C- 250 mg magnesium sulfate, Group D- 1 μg/kg dexmedetomidine.

Duration of analgesia was significantly prolonged, onset of sensory and motor blockade was hastened and analgesic requirement was reduced in a dose responsive manner (for magnesium group), without causing clinically significant and unmanageable side effects. Intensity of potentiation was higher with dexmedetomidine than magnesium sulfate.

Magnesium sulfate potentiates supraclavicular block in a dose dependent manner. Potentiation by dexmedetomidine is greater than that by magnesium sulfate.

Keywords

Dexmedetomidine, Magnesium sulfate, Supraclavicular block, Ropivacaine