International Journal of Contemporary Microbiology
  • Year: 2017
  • Volume: 3
  • Issue: 2

A Study of Blood Storage Related Biochemical Changes in CPDA-1 Anticoagulant Containing Blood Bags

  • Author:
  • Bilal Khan1, Kalpana Sankhala2,6, Arvind K Shukla3, Sartaj Ahmad4, Amir Khan5
  • Total Page Count: 4
  • Page Number: 10 to 13

1Lecturer, Department of Paramedical Sciences, Subharti Medical College, Meerut, UP

2Professor, Department of Pathology, NIMS Medical College

3Assistant Professor, (Biostatistics), Subharti Medical College, Meerut, UP

4Associate Professor (Medical Sociology), Department of Community Medicine, Subharti Medical College, Meerut, UP

5Post Graduate Nursing, Panna Dhai Maa Subharti Nursing College, Meerut, UP

6Medical Officer/In charge Blood Bank, NIMS Hospital, NIMS University, Shobha Nagar, Jaipur, Rajasthan

Online published on 4 November, 2017.

Abstract

The study was aimed to compare biochemical changes in stored blood in CPDA-1 containing blood bags, in relation to different time periods ranging from 1 to 35 days. The present study was conducted at Blood Bank of NIMS Hospital, Jaipur to determine the biochemical changes in stored blood at 4–6°C in fifty CPDA-1 containing blood bags.

All blood donors were male, voluntary or replacement and were tested negative for HIV 1&2, HCV, HbsAg, Syphilis and Malaria. Biochemical parameters are measured by Trivitron fully auto analyzer. Electrolytes are measured by fully auto analyzer ISE 3000 made in France. All biochemical parameters showed significant changes. There was reduction in glucose and sodium levels, while on comparing other biochemical parameters from day 1 to day 35, there was marked increase in levels of calcium from 8.11 to 15.3 mg/dl, phosphorous from 7.8 to 15.7, potassium from 4 to 25.3, chloride from 81.9 to 98.9 mg/dl, total protein from 5.2 to 8.2 gm/dl and albumin from 2.5 to 5.7 gm/dl. Therefore old blood should not be used for the treatment of anemia.

Keywords

Stored blood, Blood bank, Biochemical, Parameters, Whole blood, Storage