International Journal of Contemporary Pathology
  • Year: 2016
  • Volume: 2
  • Issue: 1

Cord Blood Screening of Haemoglobinopathies in the Newborn from North East India

1Senior Resident, Department of Pathology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong-793018, Meghalaya, India

2Professor & Head of the Department, Department of Pathology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong-793018, Meghalaya, India

3Associate Professor, Department of Pathology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong-793018, Meghalaya, India

4Professor & Head, Department of Obstetrics and Gynaecology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong-793018, Meghalaya, India

*Corresponding author: Dr Vandana Raphael, Professor & HOD, Department of Pathology, (NEIGRIHMS), Mawdiangdiang, Shillong-793018 Email: raphaellyngdoh@gmail.com Phone: +919436707442, Fax: 03642538008

Online published on 13 June, 2016.

Abstract

Thalassaemia and haemoglobinopathies are major public health problems worldwide. Among them HbE is common in South East Asia, prevalence reaching up to 30–40%. In the present study, 117 (23.21%) babies out of 504 showed the presence of haemoglobinopathies with Haemoglobin E heterozygous being the commonest form. We emphasize the need for an appropriate screening strategy for early diagnosis.

Keywords

Cord blood, hemoglobinopathy, HPLC