1Assistant Professor, Department of Veterinary Anatomy and Histology, Arawali Veterinary College (Affiliated with Rajasthan University of Veterinary and Animal Sciences, Bikaner), Rajasthan, India
2Associate Professor, Department of Veterinary Microbiology, Arawali Veterinary College (Affiliated with Rajasthan University of Veterinary and Animal Sciences, Bikaner), Rajasthan, India
3Associate Professor, Department of Animal Genetics and Breeding, Arawali Veterinary College (Affiliated with Rajasthan University of Veterinary and Animal Sciences, Bikaner), Rajasthan, India
4Assistant Professor, Department of Livestock Products Technology, Arawali Veterinary College (Affiliated with Rajasthan University of Veterinary and Animal Sciences, Bikaner), Rajasthan, India
5Assistant Professor, Department of Veterinary Gynaecology and Obstetrics, Arawali Veterinary College (Affiliated with Rajasthan University of Veterinary and Animal Sciences, Bikaner), Rajasthan, India
6Assistant Professor, Department of Veterinary Public Health and Epidemiology, Arawali Veterinary College (Affiliated with Rajasthan University of Veterinary and Animal Sciences, Bikaner), Rajasthan, India
*Corresponding author: Dr. Subha Ganguly Senior Hony. Editorial/Advisory Board Member (IJOCP); Email: ganguly38@gmail.com
Online published on 13 June, 2016.
In AIDS patients, the main opportunistic infections are related to intracellular agents like P. carinii, cytomegalovirus, C. albicans, M. tuberculosis and criptosporidium. As in HIV infection, memory B lymphocytes keep functioning, antibodies are produced and the protection mechanism against extracellular agents does not experience large scale damage. However, this lack of greater susceptibility to extracellular bacterial infections observed in AIDS patients is observed in adults where the repertory of B-cell produced antibodies depending on T-cells had already formed prior to HIV infection. In infected children, as the alteration of TCD4+ cell functioning is premature, cellular cooperation is damaged with abnormalities also occurring in the synthesis of antibodies. Infections by extracellular bacteria are common in HIV-infected children.
AIDS, HIV, Immune response
