Study of pernicious anemia in females of Maharashtra population

In the present study 60 adult females suffering with pernicious Anemia aged between 20–50 years were studied. Their neurological signs due to vitamin B12 deficiency were touch in 10 females i.e. 3(5%) in upper limb. and 7(11.6%) in lower limb. Reflex was in 22, 5(8.3%) in UL and 17(28.3%) in lower limb. position 18, 3(5%) in upper limb and 15(25%) in lower limb. Vibration was in 10, 2 (3.3%) in upper limb and 8(13.3%) in lower limb. Clinical symptoms were chronic headache in 12(20%) females, palpitation 6(10%), giddiness 20(33.3%), altered bowel habit 8(13.3%). Tingling 10(16.6), ataxic gait 4(6.6%). The clinical problems were pallar 25(41.6%) stomatatis 15(25%), glossitis 11(18.3%), hyperpigmentation of skin 9(15%). This study of vitamin B12 deficiency with various clinical manifestations will be useful for pathologist and clinician to correlate the level of vitamin B12 and its outcome of deficiencies; moreover this new study will have inven-tive thought because exact cause of failure of vitamin B12 absorption is still obscure.