International Journal of Contemporary Pathology
  • Year: 2018
  • Volume: 4
  • Issue: 2

Study of Cerebro-Spinal fluid in HIV patients in both sexes of Maharashtra population

1Associate Professor, Department of Pathology, Raipur Institute of Medical Sciences, Raipur, Chhattisgarh State

2Assistant Professor, Department of Pathology, Raipur Institute of Medical Sciences, Raipur, Chhattisgarh State

*Corresponding author: Rajesh P Loya Assistant Professor, Department of Pathology-Raipur Institute of Medical Sciences, Raipur-492006 (Chhattisgarh State)

Online published on 6 September, 2018.

Abstract

In the present study 45 males and 45 females aged between 20–40 years infected with HIV were selected for study. The weight of male 30(66.6%) were between 39–45 kg, 15(33.3%) were between 46–55 kg and females 25(55.5%) were between 39–45.kg and 20(44.4%) were between 46–55 kg. The serum creatanine value was 0.80 to 0.90 in 25(55.5%) 0.90 to 1.00. 20(44.4%) in males. In females 28(62.2%) had 0.80 to 0.90, 17(37.7%) had 0.90 to 100 (μ mm) CD4 count was in 23 (51.1%) 0.83 to 100 and in 22(48.8%) 101 to 140 in males and in females 24(53.3%) had 83 to 100, 21(46.6%) had 101 to 140 CD4 count also noted. The clinical symptoms were headache 16(35.5%) in males 18(40%) in females. Fever in males 8(17.7%) in females 5(11.1%), mental confusion 5(11.1%) in males, 7(15.5%) in females, vomiting 9(20%) in males, 10(22.2%) in females, dizziness 4(8.8%) in males, 3(66%) in females, seizures. 3(6.6%) in males, 2(4.4%) in female. The associated diseases noted in HIV patients were TB 12(26.6%) in males, 14(31.1%) in fe-males, candid 25(55.5%) in males, 20(44.4%) in females, diarrhea 6(13.3%) in males, 8(17.7%) in females, pneumonic 2(4.4%) in males, 3(6.6%) in females. The abnormalities of CSF was protein 30(66%) had 75–80 15(33.3%) had 85–95 in males 29(64.4%) had 75–80, 16(35.5%) had 85–95 in females cells 3(71.1%) had 6–8, 13(28.8%) had 7–5 cells in males, 30, (66.6%) had 6–8 cells 15(33.3%) had 7–5 cells in females. Indian Ink staining 15(33.3%) had 20–26, 30(66.6%) had 25–19 in males cryptococcal antigen titre-22(48.8%) had 5–10, 23(51) had 3–4 in males, 23(51%), 22(48.81%) had 3–4 cells in females. Culture base line was 39 (86.6%) had 27–29, 16(13.3%) had 20–26, in males, 40(88.8%) had 27.29, 5(11.1%) had 20–26 culture observed in female at base line. This study of CSF in HIV patients will be quite useful to pathologist and clinician to correlate the obtained values.

Keywords

HIV, Cryptococcus Meningitis, Tuberculosis Meningitis, Candia