1Senior Resident, Dept. of Biochemistry, Govt. Medical College, Bettiah
2Senior Resident, Dept. of Medicine, Patna Medical College, Patna
3Specialist Medical Officer, Obstetrics and Gynaecology, Bihar Sharif
4Consultant (DM Gastroenterologist), Curis Hospital, Patna
Online published on 17 July, 2019.
In non-insulin dependent diabetes mellitus, dyslipidemia is prevalent and major risk factors for coronary artery disease. Maintaining tight glycemic along with lipid control plays an essential role in preventing micro- and macro- vascular complications as well as cardiovascular risk associated with diabetes. This study was designed to highlight the relationship between glycosylated hemoglobin (HbA1c) and triglyceride levels.
Hundred (100) diagnosed cases of type 2 Diabetes Mellitus of either sex and age >18 years were selected for this study. Demographic information and medical history were taken. Venous samples of patients were collected after 12-hour fasting for measurement of triglyceride levels and glycated hemoglobin (HbA1c) for 6 months. Statistical analysis of data obtained were done through Graph Pad Instat software.
High triglyceride in comparison to four different cut offs of HbA1c like 7%, 8%, 9% and 10% was 26%, 48%, 69% and 78% respectively. High level of HbA1c showed a significant association with high triglyceride levels at p <0.001. Demographic factors (age, race, gender), lifestyle factors (smoking, body mass index, lifestyle) and health status factors (blood pressure, physician-rated health status) had correlation with the different cut offs of HbA1c on comparison.
Glycated hemoglobin was positively correlated with high triglyceride. Hence, HbA1c can be an indicator of triglyceride level and can be one of the predictors of cardiovascular risk factors in type 2 diabetes mellitus.
Diabetes, HbA1c, triglyceride, dyslipidemia, cardiovascular event
