Veterinary Control and Research Institute, 42080, Meram, Konya, TURKEY.
*Telephone: +90 332 322 4741, Fax: +90 332 320 37 98, E-mail: ertanoruc@hotmail.com or ertanoruc@yahoo.com
Multisystemic enlargement of lymph nodes and some parenchymal organs were observed in 7 months old Holstein calf. Tumor cells were prolymphocytic poorly differentiated type and probably not originated from B cells. It was cytologically diagnosed as malignant round cell tumor. Histopathological examination revealed that lymph nodes, liver, spleen were all extensively infiltrated by small to large sized, lymphocytic and lymphoblastic cells with low mitotic index. Methyl green pyronine histochemistry for B cells and serological diagnosis of enzootic bovine leukosis by ELISA was negative. It was described as calf type Sporadic Bovine Leukosis.
Sporadic bovine leukosis, calf, cytology, pathology, histochemistry