A Comparative Study of the Anti-inflammatory effect of Topical 1% Prednisolone and Topical 0.1% Dexamethasone Eye Drops after Cataract Surgery in Western Uttar Pradesh

The aim of this study is to compare the anti-inflammatory efficacy of topical 1% prednisolone acetate and topical 0.1% dexamethasone sodium eye drops after uneventful small incision cataract surgery with posterior chamber intraocular lens implantation in patients of Western Uttar Pradesh.

This study was done at Saraswathi Institute of Medical Sciences (SIMS) Hapur. Data was collected from Ophthalmic OPD from October 2012 to March 2013.72 patients who underwent uneventful small incision cataract surgery with posterior chamber intraocular lens implantation were taken for both study groups. The baseline parameters were same for both groups of patients. All the patients were followed up post operatively on day 1, day 3, 1 week, 2 week, 4 week and 6 weeks and post inflammatory response was graded according to severity. The anti-inflammatory efficacy of two study groups was compared by examination of operated eyes for anti-inflammatory response and visual acuity.

All results were correlated with final visual outcome, which showed that topical prednisolone acetate is clinically and statistically more effective than dexamethasone sodium in early post operative period to control the inflammation in uneventful small incision cataract surgery with posterior chamber intraocular lens implantation.

This study conclude that topical 1% Prednisolone acetate is more effective than topical 0.1% Dexamethasone sodium eye drops in controlling postoperative inflammation and early visual rehabilitation after uneventful small incision cataract surgery with posterior chamber intraocular lens implantation.