Peripancreatic Unicentric Castleman's Disease: A Case Report

Castleman's disease is a morphologically distinct form of lymph node hyperplasia. The disease is rare and the etiology remains poorly understood. Three morphological variants of the disease are described- hyaline vascular, plasmacytic and a mixed variant. Clinically, the presentation of the disease is heterogeneous. Most often, the disease presents as a localized lymph node enlargement, referred to as the unicentric type and the multicentric form is rare. In unicentric disease, surgical resection is usually curative, however in the multicentric form the management is poorly defined and the disease has a more fatal outcome. We present a case of 48 year old female presenting with peripancreatic unicentric Castleman's disease involving peripoartal lymph nodes.