International Journal of Contemporary Surgery
  • Year: 2016
  • Volume: 4
  • Issue: 1

Role of Transdermal Nitroglycerine Patch as Tocolytic in Preterm Labour

1Assistant Professor, Department of Obstetrics & Gynecology, The Oxford Medical College Hospital & Research Centre, Bangalore

2Professor, Department of Obstetrics & Gynecology, The Oxford Medical College Hospital & Research Centre, Bangalore

*Correspondence address: Dr. Saboora Bivi, Assistant Professor, Department of Obstetrics & Gynecology, The Oxford medical college hospital & Research centre, 132, 6th Cross, Bilekahalli Layout, Bannerghatta road, Bangalore-560076

Online published on 18 February, 2016.

Abstract

Objective of this study was to Study the effectiveness of transdermal nitroglycerine patch as short term tocolytic and to find the mean prolongation of gestation

The study was a Hospital based prospective study undertaken in the department of Obstetrics and Gynecology, MVJ Medical College &Research Hospital, Hoskote, Bangalore between October 2011 to September 2013. After fulfilling the inclusion and exclusion criteria a total of 50 cases were treated with transdermal Nitroglycerine patch for tocolysis.

Success rate for acute tocolysis was 74%. Mean prolongation of pregnancy was 15.1 days and mean birth weight of babies was 2.1654 kilograms. Most common side effect with Nitroglycerine patch was headache (12%).

Transdermal Nitroglycerine patch is effective for suppression of preterm labour. Most common side effect is headache.

Keywords

Preterm labour, perinatal mortality, perinatal morbidity, tocolytic therapy, antepartum glucocorticoids