International Journal of Contemporary Surgery
  • Year: 2016
  • Volume: 4
  • Issue: 1

Castleman's Disease—A Case Report and Literature Review

1Resident, Department of General Surgery, Subharti Medical College, Meerut, U.P., India

2Assistant Professor, Department of General Surgery, Subharti Medical College, Meerut, U.P., India

3Resident, Department of Radiodiagnosis and Imaging, Subharti Medical College, Meerut, U.P., India

4Professor and Head, Department of General Surgery, Subharti Medical College, Meerut, U.P., India

Online published on 18 February, 2016.

Abstract

Castleman's disease is a rare clinicopathological entity characterized by non-neoplastic lymph node hypertrophy. Its incidence and etiology is unknown. It has been found in association with Kaposi's sarcoma thus necessitating investigations for HIV. Although its localized variety is benign other types can be multifocal with adverse systemic manifestations. A case report of a 16 yrs old male with a slowly enlarging highly vascular mass in the right thigh is presented which lead to a histological diagnosis of this rare condition. Furthermore its clinical features, its types, relevant investigations and current treatment modalities are discussed.

Keywords

Castleman's disease, Kaposi's sarcoma, HIV, Lymph nodes