A Clinico-pathological Study on Gall Stone Disease

To find out the correlation among clinical presentation, Ultrasound findings, histopathological findings and presence of bacteria in bile of GSD.

We prospectively reviewed 167 patients, who underwent open or laparoscopic cholecystectomy. The clinical correlations were analyzed between clinical presentation, Ultrasound findings, histopathological findings and presence of bacteria in bile of GSD.

Over a period of one year, 167 patients with symptomatic gallstones were admitted for cholecystectomy. Most of the patients presented with recurrent abdominal Pain (81%). Vomiting and dyspepsia were found to be non specific. Fever, leucocytosis and thick walled gb were more commonly associated with ac. Bile was sent for culture intraoperatively about 35% culture showed bactibilia with most common organism being E coli. All specimens were sent for histopathology. 142 of the specimens showed evidence of chronic cholecystitis, 25 acute cholecystitis.

Acute abdominal pain, fever and leucocytosis is correlated well with thickened gb wall. Vomiting and dyspepsia cannot be correlated with severity of disease. Bile infectivity cannot be correlated with clinical presentation of GSD, thickened gall bladder wall, number of gall stones and severity of disease. Ultrasound remains the sensitive investigation for diagnosing AC with sensitivity of 83% and specificity of 87% in diagnosing AC.