International Journal of Drug Regulatory Affairs
  • Year: 2020
  • Volume: 8
  • Issue: 4

Understanding OECD guidelines for qsar models-a software development and harmonization strategy

Associate Professor, RBVRR Women’s College of Pharmacy, Barkatpura, Hyderabad-500 027, Telangana State, India

*Corresponding author Tel.: +91-9440763781, E-mail address: drbayyasubbarao@yahoo.com (Subba Rao Bayya)

Online published on 24 May, 2021.

Abstract

Post GATT era has turned towards harmonization processes not only relating to trade, services, and taxation but also towards research processes to some extent. The current guideline especially helps in developing software that helps end users of software in overcoming ambiguities and come to a faster acceptance of the research by the authority. The objective of harmonization is to minimize time, expenditure, experimental animals, scrutiny and approval processes. The current article is to know how the Quantitative Structure Activity Relationship research is made uniform for the research community by developing a policy/guideline as an international standard setting.

Keywords

OECD, Guidelines, QSAR, QSAR Validation Process, Cooper Statistics, Receiver Operating Characteristic curve (ROC)