1Department of General Biology and Genetics, Institute of Biochemical Technologies, Ecology and Pharmacy, V I Vernadsky Crimean Federal University, Simferopol, 295007, Republic of Crimea, Russia
2Laboratory of Entomology and Phytopathology, Dendrology and Landscape Architecture, Nikita Botanical Gardens - National Scientific Centre of the Russian Academy of Sciences, Yalta, 298648, Republic of Crimea, Russia
*Email: pcr.product@gmail.com (corresponding author):
Online published on 13 March, 2026.
Laboratory and field experiments have been conducted by our team since 2008 and formed the basis for these brief practical recommendations for the use of oligonucleotide insecticides (briefly, olinscides or DNA insecticides) for insect pest control in forests and agrocenoses. Most technological innovations start out very expensive and don't work well, but eventually start working well and become very cheap. Contact unmodified antisense DNA biotechnology (CUADb) has come a long way for 17 years and is very close to the point to be implemented globally on a large scale against sternorrhynchans (for example: euonymous scale Unaspis euonymi Comstock, holly scale Dynaspidiotus britannicus Newstead, soft scale Coccus hesperidum Linnaeus, cottony cushion scale Icerya purchasi Maskell, bay sucker Trioza alacris Flor, etc.), spider mites (for example: two-spotted spider mite Tetranychus urticae Koch), and other pest groups. These recommendations will help scientists with their research on oligonucleotide pesticides and also farmers around the world to use oligonucleotide insecticides and oligonucleotide acaricides more efficiently after registration.
Contact unmodified antisense DNA biotechnology (CUADb), DNA containment mechanism, Practical recommendations, DNA-programmable pest control, Eco-friendly pesticides, ‘genetic zipper’, Method