Tinospora cordifolia: A Valuable Plant in Ayurveda

Tinospora cordifolia commonly is a natural herbal shrub that belongs to the moonseed family Menispermaceae. The phytochemical analysis showed the presence of alkaloids, flavonoid, saponins, cardiac glycosides, steroids, carbohydrate and proteins. The aqueous extracts of Tinospora cordifolia were evaluated for antibacterial activity against standard pathogens i.e. Staphylococcus aureus, Escherichia coli, Vibrio cholera, Salmonella typhi, Shigella at concentrations 5, 10 and 20%. The 20% aqueous extract of Tinospora cordifolia showed an optimum zone of inhibition. Vibrio cholera MTCC 3906 was highly sensitive to aqueous extract followed by S. aureus MTCC 3160 , Salmonella enterica typhi MTCC 734 , Shigella sonnei, Escherichia coli MTCC 1018. Salmonella enterica typhi MTCC 734 was highly sensitive to methanol extract followed by Shigella sonnei, Staphylococcus aureus MTCC 3160 , Vibrio cholera MTCC 3906 , Escherichia coli MTCC 1018. These phytochemical data analysis and antibacterial activity of Tinospora cordifolia may be useful and may be lead to the improvement and formulation of drugs and discovery of drugs development against tested gastrointestinal tract pathogens.