Comprehensive Analysis of Anti-microbial Activity in Nerium oleander L. Latex Extracts

This study explored the antibacterial and antifungal potential of Nerium oleander latex extracts. In antibacterial tests, Staphylococcus aureus and Pseudomonas aeruginosa exhibited superior inhibition zones in acetone extracts, while Bacillus subtilis and Proteus vulgaris showed inhibition in diethyl ether extracts. The diethyl ether extract surpassed the standard drug tetracycline against Proteus vulgaris. All extracts demonstrated maximum inhibition at a 15% concentration. In antifungal evaluations against Aspergillus niger, Fusarium oxysporium, and Penicillium sp, acetone, chloroform, and diethyl ether extracts displayed significant inhibition zones, with concentrations correlating positively with inhibition size. This concentration-dependent relationship indicates Nerium oleander latex extracts’ potential as a valuable resource for diverse phytopharmacological activities, suggesting promising applications in future disease treatments.