Groundwater contamination of arsenic is one of the major causes of serious health hazards in many countries and has taken the dimension of an epidemiological problem. The present investigation was therefore undertaken to study the effect of sodium arseniteon haematological parameters liver and kidney marker enzymes of male albino ratsfor 30, and 60 days.
Animals exposed for two different doses (low and high) of sodium arsenite showed significant decrease of TEC, TLC, Hb and PCV (P<0.05) and increase of MCV and ESR (P<0.05) in 30 days exposed animals. Albino rats exposed for 60 days showed significant fall(P<0.05) in all these parameters except ESR. The present study also shows that there was significant increase (P<0.05) in serum creatinine, urea, alkaline phosphatase (ALP), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) values in animals exposed to sodium arsenite for 30 and 60 days in different doses compared to control.
Sodium arsenite, haematological parameters, liver, kidney and enzymes
