Assessment of Toxicity of Mercuric Chloride in Terms of Body Weight, Liver Weight and Ratio of Liver Weight/Body Weight in Albino Rat

The assessment of changes in physical parameters of biological tissues is an important way in the study of toxicity of heavy metals. It is the study which evaluate toxic effects of mercuric chloride in terms of body weight, liver weight and liver weight/body weight ratio in albino rats after acute and sub-acute treatment of it. For experiment the rats were grouped into 4 sets; one acute & 3 sub-acute (7, 14 and 21 days) and each set considered 4 rats. Control sets were runs simultaneously with each treated set. Body weight show very highly significant decrease in prior two treatments whereas liver weight show highly significant decline through the experiment. Ratio of liver weight/body weight decrease highly significant during prior 3 treatments and very highly significant in last treatment. Mercuric chloride is a systemic poison and whole animal get affected even very minute intake of it.