The present study suggest that, Aegle marmelos and Eclipta alba were shows the significant variations in the observed biochemical parameters. The level of TBARS in ethanol intoxicated rats increased two fold when compared with the control animals. The levels of GSH, SOD and CAT decreased significantly in the ethanol intoxicated rats. The level of GPx was increased in the ethanol intoxicated rats. The value of vitamin E in both plasma and liver samples were less when compared with the control animals. Similarly, the value of vitamin C was also showed decreased level in plasma. Serum iron and copper levels were elevated to a higher level. The therapeutic administrations of Aegle marmelos and Eclipta alba leaves fme powder greatly change the biochemical parameters in the ethanol intoxicated rats and maintained well to the normal level. These results clearly suggest that, the Aegle marmelos and Eclipta alba have enormous hepatoprotective value. Among the two plants Aegle marmelos has slightly high activity as compare to Eclipta alba. These herbal drugs have equivalent therapeutic value with the standards drug Silymarin. Moreover, it is very important to study the specific phytochemical compounds responsible for this hepatoprotective effect.
Aegle marmelos, Eclipta alba, hepatoprotective activity
