1Associate Professor, Department of Forensic Medicine and Toxicology, GMERS Medical College, Gandhinagar, Gujarat
2Tutor, Department of Bio-chemistry, Dr. M.K. Shah Medical College and Research Centre, Chandkheda, Ahmedabad
Online published on 27 July, 2017.
Determination of time of death is a critical step in most homicide or un-witnessed death investigation. However, the various methods currently used in estimating PMI yield large post-mortem windows and sometimes contradict one another. Pericardial enzyme is the useful biochemical markers to evaluate the postmortem interval. According to previous study, many authors have demonstrated the high significant relationship between the time since death and various body fluids in human.
Present study is carried out to detect the significant biochemical markers which are helpful to detect the postmortem time interval after death from pericardial fluid. Analysis of pericardial fluid from 90 subjects shows that the enzymes activity of creatinine phosphokinase, Gamma glutamyl transferase, Amylase and lactate dehydrogenase has statistically significant (p< 0.0001) and it's positively correlate to postmortem interval up to 36 hours of death.
creatinine phosphokinase, amylase, Lactate dehydrogenase, GGT, time of death, postmortem intervals
