Indian Journal of Forensic Medicine & Toxicology
  • Year: 2017
  • Volume: 11
  • Issue: 2

Integrated MOSFET-Embedded Cantilever Sensor Diagnostic System using MEMS in Biomedical

1Research Scholar, Department of Electrical and Electronics Engineering, ARM College of Engineering & Technology, Chennai

2Professor, Department of Electrical and Electronics Engineering, ARM College of Engineering & Technology, Chennai

Online published on 4 November, 2017.

Abstract

Recent advances in nanotechnology ensure broad and reasonable potential for the change of imaginative and predominant recognizing and demonstrative procedures in biomedical field. In particular, the scaled down scale cantilever area perspective in light of direct transduction of nuclear limiting actuated surface stress into a nano-mechanical development of little scale cantilevers has pulled in noteworthy thought for stamp free acknowledgment of biomolecules. As another choice to the directly sent optical, piezoresistive, and capacitance nanomechanical acknowledgment strategies, we display another electronic transduction perspective including two-dimensional littler scale cantilever shows with geometrically organized metal-oxide semiconductor-field-affect transistors (MOSFETs) introduced in the high tension district of the scaled down scale cantilevers. We have shown that the redirection of the scaled down scale cantilever provoked by specific ligand-analyte limiting events prompts a correct, quantifiable and reproducible change in the exhaust current of the MOSFET shrouded in the little scale cantilevers. High present affectability of MOSFET embedded stage engages perceiving nano-scale cantilever redirection from specific biomolecular confining events at low centralization of analytes with affectability in the parts-per-trillion region. We have shown ultra-unstable acknowledgment of streptavidin-biotin based biomolecular affiliations and biomarkers for cardiovascular ailments. Our novel acknowledgment parts offer a splendid stage for variety of different biomolecular recognizing applications, stretching out from clinical diagnostics and common checking to prescription disclosure, and moreover gas and substance identifying by organizing receptors on MOSFET cantilevers.

Keywords

MOSFET-Embedded, cantilever, MEMS, Biomedicine