Indian Journal of Forensic Medicine & Toxicology
  • Year: 2018
  • Volume: 12
  • Issue: 2

Association of Barbiturates in Biological Activities as a Toxicological Agent

1Assistant Professors (Ad-hoc), Department of Forensic Science, School of Life Sciences, Guru Ghasidas Vishwavidyalaya(A Central University), Bilaspur (C.G.)

2Professors, Department of Chemistry, School of Chemical Sciences, Dr. H S Gour University Sagar (A Central University), (M.P.)

*Corresponding author: Dr. Sudhir Yadav Assistant Professor (Adhoc), Department of Forensic Science, School of Life Sciences, Guru Ghasidas Vishwavidyalaya(A Central University), Bilaspur (C.G.),. E-mail: sudhirforensic@gmail.com Mob. No. +918889402569

Online published on 5 May, 2018.

Abstract

Barbiturates are known to have toxic activities on the body and are also known to affect the metabolic activities. They are weak acids, soluble in organic solvents and can be extracted from aqueous media. Therefore, they are generally classified as organic non-volatile substances extractable from acid solutions and are included in the schedule of NDPS Act. They are mainly termed as hypo-sedatives under the psychoactive group of drugs. A sedative is a drug, which is used to allay a patient and to make him drowsy without actually inducing sleep, where a hypnotic is a drug, which produces sleep. Therapeutically, they are used as sedatives, hypnotics, anaesthetics, and anticonvulsants. Biological activity shown by any molecule has been considered to be an individual or collective nature of the constituting atoms and/or substituent. Toxicological studies of rare-earth elements are very difficult because they were contaminated with other similar elements making interpretation of the results difficult. Therefore, in the present article by keeping above facts in mind the author has discuss the Barbiturate toxicity and various biological activities associated with it from reading secondary data sources i.e. e-books, research publications and various toxicological reports etc.

Keywords

Barbiturates, Rare earth elements, Toxicity, Biological Activity etc