Indian Journal of Forensic Medicine & Toxicology

  • Year: 2019
  • Volume: 13
  • Issue: 2

Histological & Physiological Alternations in the Aorta & Heart in Relation with Cholesterol Diet in Male Albino Rat

  • Author:
  • Muna Hussain AL-Aameli1,, Rajaa Ali Moheiseen Al-Taee2, Heba A. Abd-Alsalam Alsalame3
  • Total Page Count: 6
  • Page Number: 301 to 306

1College of Veterinary Medicine, Kerbala University, Iraq

2College of Medicine, Babylon University, Iraq

3College of Education for Pure Science, Kerbala University, Iraq

Abstract

The aim of this work was to examine the microscopically alterations in the heart architecture & of albino rat & physiological aspects of lipid profile in relation with cholesterol diet. Ten male of albino rats were subdivided into two groups (n=5): group 1 was given 1 ml of normal saline & considered as control group(G1), while the second group treated with enriched-cholesterol nutriment once at a dosage of 1.5 mg/k g body weight extent to 8 weeks & considered as treated group(G2). The tissues of hearts & aortic were obtained & stained with H & E stain. Blood samples were withdrawn after starvation of the animals at night after the end of the experiment to study the following parameters: measurement the intensification of (T C), (T A G), (H D L), (L D L) & (V L D L). Result showed the presence of a significant increase (p < 0. 0 5) in the concentrations of TC, TAG, LDL, VLDL & significant decrease (p < 0.0 5) in the concentrations of HDL in processed group (G2).

Keywords

Cholesterol, histology, physiology, heart, aorta