Indian Journal of Forensic Medicine & Toxicology

  • Year: 2019
  • Volume: 13
  • Issue: 2

Histological & Physiological Alternations in the Aorta & Heart in Relation with Cholesterol Diet in Male Albino Rat

  • Author:
  • Muna Hussain AL-Aameli1,, Rajaa Ali Moheiseen Al-Taee2, Heba A. Abd-Alsalam Alsalame3
  • Total Page Count: 6
  • Page Number: 301 to 306

1College of Veterinary Medicine, Kerbala University, Iraq

2College of Medicine, Babylon University, Iraq

3College of Education for Pure Science, Kerbala University, Iraq

*Corresponding author: Muna Hussain AL-Aameli. College of Veterinary Medicine, Kerbala University, Iraq

Online published on 7 May, 2019.

Abstract

The aim of this work was to examine the microscopically alterations in the heart architecture & of albino rat & physiological aspects of lipid profile in relation with cholesterol diet. Ten male of albino rats were subdivided into two groups (n=5): group 1 was given 1 ml of normal saline & considered as control group(G1), while the second group treated with enriched-cholesterol nutriment once at a dosage of 1.5 mg/k g body weight extent to 8 weeks & considered as treated group(G2). The tissues of hearts & aortic were obtained & stained with H & E stain. Blood samples were withdrawn after starvation of the animals at night after the end of the experiment to study the following parameters: measurement the intensification of (T C), (T A G), (H D L), (L D L) & (V L D L). Result showed the presence of a significant increase (p < 0. 0 5) in the concentrations of TC, TAG, LDL, VLDL & significant decrease (p < 0.0 5) in the concentrations of HDL in processed group (G2).

Keywords

Cholesterol, histology, physiology, heart, aorta