Indian Journal of Forensic Medicine & Toxicology
  • Year: 2019
  • Volume: 13
  • Issue: 2

Effects of Dietary Grape Seed Extract on Physiological Parameters, Antioxidant Activity and Immunological Status of Broiler Chicks Exposed to Aflatoxin

1Physiology, Biochemistry and Pharmacology Department, College of Veterinary Medicine, University of Kerbala, Iraq

2Pathology and Poultry Diseases Department, College of Veterinary Medicine, University of Kerbala, Iraq

*Corresponding author: Ala'a S. Almusawi, Physiology, Biochemistry and Pharmacology Department, College Of Veterinary Medicine, University of Kerbala, Iraq

Online published on 7 May, 2019.

Abstract

Major target of the study was inspection of the protecting role of grape seed extract (GSE) in alleviating the physiological changes of broiler chicks during exposure to aflatoxins in contaminated feed. One hundred &twenty five broiler chicks ‘‘ Ross’’ 308 (1d-old) were used, Birds were randomly divided into 5 groups, (25 birds for each group). Birds in group1fed on normal diet as a control. Birds in group 2 fed on normal diet with (200mg/kg GSE). Birds in groups 3 fed on contaminated diet (AF+200mg/kg GSE). Birds in group 4 fed on contaminated diet (AF+100mg/kg Mycofix). Birds in group 5 fed on contaminated diet(AF only)without any treated. the results showed the addition of (G S E) lead to a significant rise (P≤0.05)in antioxidant rates(GPx) &in the levels of antibodies against (N D & I B D), as well which exposed a significant reduction (P ≤ 0. 0 5) of the physiological indicators (AST, ALT) & in MAD, in group 3 while the result in treated (AF only) in group 5 there are converse all the results in the same parameters.

Keywords

G S E, Aflatoxin, Antioxidant, Immunity, Broilers