Indian Journal of Forensic Medicine & Toxicology

  • Year: 2019
  • Volume: 13
  • Issue: 3

Systematic Analysis and Meta-Analysis of Obesity, Hypertension, and Diuretic Use as Double Risk Factors for Incident Gout

Ministry of Public Health, Maysan Health Department, Maysan Governorate, Iraq

Abstract

The treatment of gout lacks the significance it requires. To reduce the incidence of there is need to identify incident gout in populations. The study analyses obesity, hypertension, and diuretic use as risk factors for incident gout. The study applies a descriptive design. The study did a systematic review and meta-analysis of cohort studies in an adult population with the minimum age for participants being aged 18 years. The study identified 9932 articles. 23 of the articles achieved the inclusion requirements and 17 of them had data that was used in meta-analysis. Obesity had four articles for publication, six for hypertension, and three for diuretic use identified to it. The use of diuretics, hypertension, and obesity use double the risk for incident gout. All these factors doubled the chance of acquiring gout in comparison to individuals outside this category. There is a need for clinicians to identify incident gout in populations and offer these populations proper treatment and management to reduce the incidence of gout.

Keywords

Meta-analysis, systematic review, gout, obesity, hypertension, diuretic use