Indian Journal of Forensic Medicine & Toxicology
  • Year: 2019
  • Volume: 13
  • Issue: 4

Role of Nanoparticles Applications as a Model in DNA Technologies; A Review

1College of Science, University of Babylon, Iraq

2College of Science for Women, University of Babylon, Iraq

*Corresponding author: Mona N. Al-Terehi Email: Monanajah1981@gmail.com

Online published on 27 November, 2019.

Abstract

Nanotechnology is one of the modern sciences that deal with nanoparticles for different applications. One of the most important using is in DNA technologies. The magnetic beads, gold nanoparticles and silica nanoparticles are used in DNA extraction; other modified magnetic nanoparticles are used for plasmids purification. Also, they are applied in DNA sequencing like NGS for fixed DNA fragments after genomic libraries. Furthermore, previous studies recorded the capability of nanoparticles in DNA storage. Gene therapy has used nanoparticles in gene transfer like gold and magnetic beads. It is also added to several buffers used in forensic applications and in amplification systems. From this review we concluded the main roles of nanoparticles are in DNA technologies which are used for medical and scientific applications.

Keywords

Nanoparticles, Magnetic beads, gold nanoparticles, DNA technologies