Study The Phytochemical Analysis and Modulatory Effects of Hydroalcoholic Extract of Morus Plant Leaves on Mental Depressive Disorder

To evaluate the antidepressant activity of hydroalcoholic extract of Morus alba leaves in mice after acute 7 days and 14 days of treatments by using two models of depression tail-suspension test (TST) and forced swim test (FST). Duration: Three months (September 2018-December 2018). Design: Observational study by using digital camera. Findings: The findings showed that the hydroalcoholic extract of Morus alba leaves at the doses of 200 and 400 mg/kg significantly (P> 0.05) reduced the immobility times in both the tests(TS & FS) as compared to control in both acute and after 14 days of treatments. The phytochemical analysis of hydroalcoholic extract of Morus alba leaves revealed the presence of alkaloids, phenols, flavonoids, Tannins, Saponins, Steroids Glycosides and Coumarins. Conclusion: It can be concluded that Morus alba hydroalcoholic leaves extract have antidepressant effect in both acute and after 14 days of treatment and there were dose dependent in increasing these effects.