Indian Journal of Forensic Medicine &Toxicology

  • Year: 2010
  • Volume: 4
  • Issue: 2

Effect of chlosite (xanthan gel with chlorhexidine) on clinical & microbiological parameters in smokers - A case series

  • Author:
  • Chetan Chandra1, Sumi Chandra2
  • DOI:
  • Page Number: to

1Department of Periodontics & Implantology, Sardar Patel Post Graduate Institute of Dental & Medical Sciences, Lucknow.

2Department of Prosthodontics, Sardar Patel Post Graduate Institute of Dental & Medical Sciences, Lucknow.

Abstract

Prevention of the periodontal disease progression is the primary goal of periodontal therapy. When conventional therapy is found inadequate to attain periodontal health in Chronic Periodontitis, local antimicrobial agents have been used as an adjunct with scaling and root planing which have reproduced encouraging results. This case series evaluates the newly released sustained local drug Chlosite clinically & microbiologically in smokers.

The patients were grouped into experimental group A treated with scaling and root planning plus Chlosite (SRP + CHL), experimental group B treated with Chlosite alone (CHL) and control group C treated only with scaling and root planing (SRP) alone. A total number of 74 sites from 3 chronic smoker patients participated in this study. The clinical parameters, Plaque index (PI), Gingival index (GI), Bleeding index (BI) and Relative attachment level (RAL), were recorded and microbiological samples taken before scaling and root planning.

All the groups, showed statistically significant reduction in relation to Plaque index, Bleeding index & relative attachment level. Combination of scaling and root planning with chlosite resulted in added benefits as compared to the two treatment groups. All the groups showed reduction in the microbial count of fusobacterium nucleatum, Porphromonas gingivalis and tannerella forsythesis.

Interpretation and conclusion: In this study all treatment groups were found to be efficacious in the treatment of periodontal disease as demonstrated by improvement in PI, GI, BI and RAL. Combination of SRP and Chlosite resulted in added benefits compared to the two treatment groups.

Keywords

Chlosite, Chronic periodontitis, xanthan gel, Smokers