1Department of Anesthesia and Intensive care, IMS, Banaras Hindu University, Varanasi, UP, India
Endosulfan is a chlorinated hydrocarbon, widely used as an insecticide. Acute poisoning can have multisystem involvement & even renal failure. We are reporting a case of endosulfan poisoning precipitating as nephrogenic diabetes insipidus (NDI), after being admitted in a state of altered consciousness, vomiting, and seizure. The diagnosis of NDI was suspected due to symptoms like polyuria and thirst, developing on the second day of admission; confirmation was done by antidiuretic hormonal essay and positive water deprivation test. We emphasize that, if there are symptoms like polyuria and thirst in a case of endosulfan poisoning, the diagnosis of NDI should be considered as one possibility when etiology is not certain.